Anesthetic drugs are present in the home medicine cabinet of almost every family. In this article, we will talk about one of the strongest such funds - Ketorola. This drug is suitable for rid of both moderate pain syndrome and severe syndrome. Let's figure out in what cases this drug will be effective, we will learn about the forms of ketorol and its analogues.
Content
Ketorol - Instructions for use
Ketorol action
Ketorol is a non -steroid anti -inflammatory drug. Its effect can be explained by a decrease in the production in the peripheral tissues of a special enzyme - cyclooxygenase, resulting in a slowdown in prostagadins. It is prostagdins that are responsible for pain, processes of inflammation and thermoregulation in the human body. Thus, the pharmacological effect of ketorol consists in creating the effect of the following types:
- anti -inflammatory effect;
- analgesic effect;
- antipyretic effect.
It is also worth noting that ketorol does not affect the course of the disease, but simply relieves some symptoms.
Ketorol - composition
The drug Ketorol is produced in various dosage forms, depending on which the composition of the drug changes. But the active substance always remains the same. Consider the composition of ketorol tablets:
- ketorolak Trometamine is the main active substance;
- cellulose;
- starch;
- magnesium stearat;
- silica;
- dyes.
Ketorol - dosage
Ketorol is a strong analgesic drug that can save even a strong pain syndrome. As when taking any other drugs, you should definitely familiarize yourself with the dosage. It is important to know what the maximum number of tablets (other dosage forms) is permissible to take during the day.
- A single dose of ketorol is 10 mg of Ketorolak Trometamine. This means that with a pronounced pain syndrome, you can take 1 tablet at a time.
- The permissible dose per day is 40 mg of trometamine ketorolac (4 tablets).
- It is advisable to take a minimum effective dose. The course of taking ketorol should not exceed 5 days.
- If there is a need to switch to the parenteral path of administration of the drug, then the daily dose of cutolac trometamine on the transition day should not exceed 90 mg. This dose is acceptable for patients aged 16 to 65 years. For people suffering from kidney diseases and people over 65, the dose should not exceed 60 mg of trometamine ketorolac. On the first day of the transition to the intramuscular method of introducing ketorol, the dose of tablets should not exceed 30 mg for all categories of patients.
- Ketorol is intramuscularly administered 1-2 ml every 6-8 hours. As a rule, this method of administration is chosen with particularly pronounced pain syndromes. The course of taking ketorol in ampoules should also not exceed 5-7 days in order to avoid side effects.
Ketorol - side effects
If you do not comply with the recommended dosage when taking the drug Ketorol, that is, a large risk of side effects. People over 65 years old or people suffering from gastrointestinal diseases have a greater chance to experience the side effect of the drug. Consider a list of possible side effects to various human body systems:
- from the side of the gastrointestinal tract, such side effects as nausea, diarrhea, vomiting, stomatitis, flatulence, acute pancreatitis, hepatitis, erosive or ulcerative lesions of the gastrointestinal tract;
- side effects such as acute renal failure, decrease or increase in urine, nephritis;
- from the part of the senses, such side effects as disorders in vision, hearing can rarely occur;
- from the side of the respiratory system, such side effects as shortness of breath, spasm of the bronchi, spasm of the larynx can be observed;
- from the side of the nervous system, side effects in the form of dizziness, drowsiness, apathy, and pain in the head can be observed quite often. Depressive conditions, hallucinations, neurotic conditions, increased nervous excitability can occur very rarely;
- from the side of the cardiovascular system, an increase in blood pressure can often be observed. Rarely can occur pulmonary edema, fainting;
- from the side of the skin, a rash, urticaria, dermatitis, itching, peeling can occur.
A person taking the drug Ketorol may have individual intolerance to this product. This can manifest itself in an increase in body temperature, the difficulty of breathing, an increase or decrease in pressure, sweating, chills, edema of a quinc, edema of some parts of the body, nausea and vomiting. If, after taking the tablet, you sharply manifested any of these symptoms, then immediately inform the doctor and do not take the next dose of the medicine.
Ketorol - contraindications
Before the use of the drug, Ketorol must be familiar with contraindications to the use of this tool:
- bronchial asthma;
- polyps in the nose or paranasal sinuses;
- the state of dehydration;
- ulcer, gastritis of the stomach or any other diseases of the gastrointestinal tract in the acute phase;
- children's age up to 16 years;
- individual intolerance to Ketorolak Trometamine - the main active substance;
- heart failure;
- renal failure;
- violations of blood coagulation;
- condition after surgery with the risk of high blood loss;
- suspicion of bleeding of any kind;
- the period of pregnancy, breastfeeding.
Ketorol compatibility with other drugs
If there is a need to use the drug Ketorol, then you need to know about the features of its interaction with some other drugs. The joint administration of some drugs can reduce the effect of one or another drug.
- The joint taking of the drug Ketorol with other non-steroidal anti-inflammatory drugs significantly increases the risk of harmful effects on the organs of the gastrointestinal tract.
- The joint use of the drug Ketorol with drugs that exert the same load on the work of the kidneys increases the effect of nephrotoxicity. Such drugs include paracetamol, methotrexate.
- It is worth avoiding the joint use of the drug ketorol with thrombolytics, anticoagulants due to the risk of bleeding.
- The joint use of the drug Ketorol with drugs to reduce blood pressure, with diuretics reduces the effect of the latter.
- With the joint use of the drug Ketorol with insulin, insulin dose correction is required.
- Ketorol with any psychostimulating drugs due to the high risk of adverse reactions from the nervous system should be avoided.
- It is worth avoiding the joint use of the drug Ketorol with anticonvulsants due to the risk of seizures.
Ketorola dosage forms
Ketorol in tablets - Instruction
Ketorol is a non -steroid anti -inflammatory drug, which, with moderate pain syndrome, is most often used in tablets. Ketorol tablets are biconvex, covered with a soluble green film shell. On one side of the tablet there is embossing the letter S. If you cut the tablet half, then in the cut you can see a white core and a thin layer of the green membrane. Ketorol tablets are sold in blisters placed in cardboard packaging.
Ketorol in injections - Instruction
Ketorol in injections is used for severe pain syndromes. In practice, this is usually used this dosage form in the postoperative period to eliminate pain. The duration of the use of ketorol in ampoules should not exceed 5 days. As a rule, from the 2nd day of intramuscular administration of this drug, patients are transferred to ketorol in tablets. Consider the composition of the ketorol solution:
- one ampoule contains 30 mg of the main active substance - Ketorolac Trometamine;
- ethanol;
- sodium chloride;
- propylene glycol;
- water, etc.
The dosage of a ketorol solution for intramuscular administration depends on the intensity of pain, patient's age, health. A single dose can be 10-30 mg of ketorolac. You always need to strive for the smallest effective dose.
Ketorol in Gel - Instruction
Ketorol is an analgesic that can be used for external use if it is represented in the form of a gel. Gel Ketorol is a transparent gel of a homogeneous consistency, which has a weak characteristic smell. This tool is used to reduce the pain syndrome for myalgia, radiculitis, bruises, neuralgias, Burit, synovitis. Consider the composition of this dosage form of ketorol:
- 1 g of gel contains 20 mg of the main active substance - cutorolac Trometamine;
- propylene glycol;
- dimethyl sulfoxide;
- trometamine;
- water;
- flavor;
- ethanol;
- glycerol et al.
It is worth noting that the drug Ketorol in the gel in the same way as in other drug forms does not affect the course of the disease. The gel must be used externally and only on dry and clean skin. Squeeze a strip of gel 1-2 cm long in place where the pain is felt most. With soft rubbing movements, you need to massage this place until the gel is completely absorbed. Next time, the Ketorol gel can only be used after 4 hours. The maximum amount of use of ketorol gel per day is 4 times. To refrain from using the ketorol gel should children under 16, women in the last trimester of pregnancy, people with skin diseases, open wounds, cuts, abrasions, people with individual cutometamine intolerance, people with bronchial asthma, and polyps in the nose.
Ketorol in ointment - Instruction
Non -steroidal anti -inflammatory drugs in the form of ointments are very convenient to use. The ointment differs from the gel in that it is created on a fat basis. Ointments usually have petroleum jelly, various oils, fat, etc. Medicines in the form of gels have a lighter texture, created on an aqueous or alcohol basis. They are absorbed faster, leaving no sensations of stickiness on the skin. Unfortunately, the drug ketorol is not available in the form of an ointment. But the modern pharmaceutical market is able to offer other non -steroidal drugs with a similar effect in this dosage form.
Ketorol in candles - Instruction
In some situations, it is very convenient to use non -steroidal drugs with a pronounced analgesic effect in the form of rectal candles. The product begins to act quickly, and also avoids direct hit in the stomach. Unfortunately, the drug Ketorol is not represented in the modern pharmaceutical market in the form of candles. If you consult a doctor, then he will certainly select for you a similar non -steroid anti -inflammatory drug in the form of candles.
Ketorol - from what helps
Ketorol with back pain
Ketorol is an effective tool for reducing pain in back pain. If the pain is not too severe, then use the dosage form for external use - Ketorol gel. It must be slowly rubbed into the most painful area on the back, waiting for complete absorption. Due to its light texture, there is no unpleasant sensation on the skin after using this gel. Ketorol in the gel begins to act after about 30 minutes. The greatest efficiency of the product is maintained for 1-2 hours, and a little less pronounced-for 4 hours. To get rid of back pain, ketorol or injections (in extreme cases), which should be used strictly according to the instructions, will be effective.
Ketorol from toothache
What could be more unpleasant for aching toothache? Pain of this kind can reach the highest threshold, bringing unbearable torment to a person. Of course, just “extinguish” symptoms with analgesic drugs is not worth it. A visit to the dentist is the first thing to think about. But situations when you have to contact painkillers are still possible. Ketorol medicine is one of the most severe products that are recommended to relieve dental pain. Due to its bright -exposed anti -inflammatory effect, toothache passes just 20 minutes after taking the tablet. Dentists recommend using this drug in cases of acute pain to relieve soreness after tooth extraction, surgical intervention in the oral cavity. But you should not postpone a visit to the doctor after delivering toothache with ketorol.
Ketorol from headache
In the indications for the use of a ketorol drug, there is also a headache. The drug blocks the production of prostagadins that are responsible for the occurrence of pain. Improving well-being occurs 15-20 minutes after taking the pill. If headaches often appear, then you should definitely find out the reason for their appearance. Just relieve pain symptoms - this is not a way out.
Ketorol from pain during menstruation
Dysmenorrhea - painful sensations in the lower abdomen in women during critical days. Someone may not have pain, someone feels moderate pains that do not bring special discomfort, and someone can reach their peak with pain. As a rule, the most severe acute pains are felt in the first days of menstruation. Ketorol is an effective drug to reduce pain. It should be taken strictly according to the instructions. It is also not allowed to take the drug Ketorol "in advance". The medicine is taken only on the fact of acute pain. It is also worth recalling that Ketorol is contraindicated for use in people under 16 years of age.
Features of the use of the drug ketorol
Ketorol to children
Ketorol is a strong drug, the use of which in childhood under 16 years old is simply unacceptable. Other drugs are used to relieve pain symptoms in children under the indicated age. Ketorol gel can be used in children over 12 years of age, and a solution of ketorol for intramuscular administration is over 15 years old.
Ketorol during pregnancy
The use of non -steroidal anti -inflammatory agent Ketorol is not recommended for pregnant women, women who are breastfeeding, during childbirth. This rule applies to ketorol in tablets and in injections. The use of ketorol gel is permissible for pregnant women on I-II trimesters of pregnancy.
Ketorol and alcohol
As for the vast majority of drugs, the combination of ketorol and alcoholic drinks is unacceptable. Consider what our body experiences when such a “powerful cocktail” enters:
- both alcohol and the drug Ketorol have a significant irritating effect on the digestive organs. With their combination, double load on the mucous membranes of the stomach, intestines;
- with a combination of the drug, ketorol with alcoholic beverages, the nature of its effect on the body changes. Ketorol is absorbed faster into the blood, as a result of which the removal of a pain symptom can occur in 10 minutes. But the excretion of the medicine from the body is accelerated, as a result of which the need to take a new dose appears faster;
- both alcohol and the drug Ketorol have a load on the liver and kidneys. With their joint administration, the load on these organs doubles.
Ketorol - reviews
- Irina Evgenievna: “There are many drugs in my home medicine cabinet, among which ketorol can always be found. This tool is a kind of emergency help with various acute pains. The husband suffers from radiculitis, and these pills are very helpful. I use ketorol for headaches. "
- Marina Ivanovna: “I met Ketorol in my youth. The fact is that during critical days my life literally stops for 1-2 days. And only thanks to this anesthetic I can continue to work without falling out of the schedule. "
- Vladimir Ivanovich: “One night, I just had an incredibly severe attack of toothache. Only one who knows what tooth pain is understanding my condition. My daughter gave a ketorol pill. I did not hope for an imminent effect, but a real miracle happened. The pain subsided, and I was able to calmly sleep until the morning. "
Ketorol is analogues
Ketorol is produced in 3 dosage forms-in tablets, in gel and in ampoules for intramuscular administration. Like most drugs, it has its own analogues. Ketorol tablets can be replaced by the following means:
- Ketanov;
- Ketarolac;
- Dolomin;
- Duba;
- Nise;
- Nurofen;
- Tempalgin.
Ketorol in ampoules for intramuscular administration can be replaced with:
- Ketanov;
- Torlac;
- Ketorolac;
- Ketolak.
Gel ketorol can be replaced with the following analogues:
- Nise;
- Diclofenac;
- Ketoprofen;
- Diclobene.
Features of the use of the drug Ketorol
- Ketorol tablets should be swallowed entirely, without grinding or chewing. Drink tablets with a small amount of water.
- Ketorol tablets can be taken both before meals and after or during. It is only worth considering that the ketorol tablet, taken after eating, will begin to act a little later.
- Ketorol is the strongest non -steroidal anti -inflammatory agent, stronger than which are only narcotic drugs.
- Do not take a ketorol drug simultaneously with other non -steroidal anti -inflammatory drugs.
- Persons suffering from violations of blood coagulation should consider that ketorol will influence the processes of blood coagulation for 1-2 days after the cancellation.
- In the elderly, the risk of side effects from taking ketorol is always higher.
- When taking the drug, Ketorol should always strive for the smallest effective dose.
- The duration of the intake of ketorol should be no more than 5 days.
- Ketorol's tablets and injections are capable of causing disorders in the nervous system. For this reason, it is recommended to refrain from driving vehicles, from working with complex mechanisms.
- If you accidentally took a large dose of ketorol than necessary, then symptoms of an overdose in the form of nausea, vomiting, acute pain in the stomach, and fainting may appear. In this case, the gastric lavage is performed and adsorbing drugs are taken.
Ketorol is an indispensable drug that can help out with acute pain of various origin. Always follow the instructions for the use of this powerful drug and store it away from the children. Ketorol is not very high, which makes an affordable drug. The presence of a prescription from a doctor to buy ketorol depends on the country where they want to buy it.
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